Searchable abstracts of presentations at key conferences in endocrinology

Endocrine Abstracts

Published by BioScientifica

Page 1 of about 1 results

ea0026p717 | Diabetes (epidemiology, pathophysiology) | ECE2011

The fed to fasting transition differentially affects PEPCK protein expression in pericentral and periportal murine hepatocytes

Herrema H , Baller J F W , Kuipers F , Groen A K , Grefhorst A

Hepatic glucose metabolism is zonated. Glycolysis is mainly localized in hepatocytes surrounding the hepatic vein (pericentral zone) whereas gluconeogenesis is mainly carried out by hepatocytes surrounding the portal vein (periportal zone). Expression of the gene encoding the gluconeogenic enzyme phosphoenolpyruvate carboxykinase (PEPCK, PCK1) is reduced upon feeding, an effect mainly controlled by insulin. PEPCK is considered a peri-portal enzyme. However, the differential ef...
0 shares

Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 | Privacy policy | Cookie settings

BiosciAbstracts

Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.

Find out more